Your privacy on IVBUSULFEX.com

This Web site is administered by Otsuka, the manufacturer of IV BUSULFEX. We want you to feel secure when visiting our site and are committed to maintaining your privacy when doing so.

The following provides an overview of how we protect your privacy during your visit.

What information do we gather?

Information on IVBUSULFEX.com is gathered in two ways: (1) indirectly (for example, through our site's technology); and (2) directly (for example, when you provide information on various pages of IVBUSULFEX.com). One example of information we collect indirectly is through our Internet access logs. When you access IVBUSULFEX.com, your Internet address is automatically collected and is placed in our Internet access logs.

We collect information directly from you in a number of ways, some of which we describe in this Privacy Statement. One way is through the use of cookies. Cookies are small files of information which save and retrieve information about your visit to IVBUSULFEX.com—for example, how you entered our site, how you navigated through the site, and what information was of interest to you. The cookies we use identify you merely as a number. (If you are uncomfortable regarding cookies use, please keep in mind you can disable cookies on your computer by changing the settings in preferences or options menu in your browser.) We also collect information when you voluntarily submit it to us. Our site may provide opportunities to contact us to ask questions or provide comments, ideas and/or suggestions. When you communicate with us and request a response, we may ask for your name and contact information. If we collect this type of information, we will notify you as to why we are asking for it and how this information will be used. It is completely up to you whether or not you want to provide it.

How do we use this information?

We analyze the information to determine what is most effective about our site, to help us identify ways to improve it, and eventually, to determine how we can tailor IVBUSULFEX.com to make it more effective. We may also use data for other purposes, which we would describe to you at the point we collect the information.

Will we share this with outside parties?

As a global organization, data we collect may be transferred internationally throughout Otsuka's worldwide organization. We will not sell individual information and will share it only with our affiliates and consultants as needed. There may be other times when we need to share information; however, before you submit any information, we will notify you as to why we are asking for it and it is completely up to you whether or not you want to provide it.

What about sensitive personal data?

We do not generally seek to collect sensitive personal data through this site. If we do seek to collect such data, we will ask you to consent to our proposed uses of the data. We may also collect some sensitive personal data incidentally. By providing us with unsolicited sensitive personal data, you consent to our using the data subject to applicable law as described in this Privacy Statement. The references to "sensitive personal data" are to the various categories of personal data identified by U.S., European and other data privacy laws as requiring special treatment, including in some circumstances the need to obtain explicit consent. These categories comprise personal identity numbers; personal data about personality and private life; racial or ethnic origin; nationality; political opinions; membership in political parties or movements; religious, philosophical or other similar beliefs; membership in a trade union or profession or trade association; physical or mental health; genetic code; addictions; sexual life; property matters; or criminal record (including information about suspected criminal activities).

What about data security?

We take appropriate steps to maintain the security of your data on IVBUSULFEX.com. You should understand that the open nature of the Internet is such that data may flow over networks without security measures and may be accessed and used by people other than those for whom the data is intended. For questions about Otsuka America Pharmaceutical, Inc. or our privacy policy, send us an e-mail.

The only FDA-approved agent for use in combination with cyclophosphamide as a conditioning regimen prior to allogeneic hematopoietic progenitor cell transplantation for chronic myelogenous leukemia (CML)

Important Safety Information At the recommended dosage, IV BUSULFEX^® (busulfan) produced profound myelosuppression in all patients (ie, severe granulocytopenia, thrombocytopenia, anemia, or a combination thereof). Frequent complete blood counts should be monitored during treatment and until recovery. Hepatic veno-occlusive disease was diagnosed in 5/61 patients and was fatal in 2/5 cases. Anticonvulsant prophylactic therapy should be administered prior to treatment. Caution should be exercised in patients with a history of seizure disorder or head trauma or who are receiving other potentially epileptogenic drugs. Bronchopulmonary dysplasia with pulmonary fibrosis is a rare but serious condition following chronic busulfan therapy. Women of childbearing potential should be advised to avoid becoming pregnant as busulfan may cause fetal harm.

The most common nonhematologic adverse events were nausea (92% mild or moderate, 7% severe), stomatitis (71% grade 1-2, 26% grade 3-4), and vomiting (95% mild or moderate), anorexia (64% mild or moderate, 21% severe), diarrhea (75% mild or moderate, 5% grade 3-4), insomnia (83% mild or moderate, 1% severe), and fever (78% mild or moderate, 3% life-threatening).

Please see Full Prescribing Information.